High Yield Topics for cracking PG Medical Entrance Exams

MyPGMEE presents High Yield Topics for fast revision that will help you prepare for PG entrance exams like AIPGMEE, DNB CET, AIIMS PG, JIPMER, UPSC.

These short topics will act as revision nuggets and aid recall during the exam, for more such tips please visit www.mypgmee.com / download mypgmee app. Join our Facebook group: crack AIPGMEE with Dr. Mudit Khanna to interact with Authors and fellow Students.

MyPGMEE Authors: Dr. Mudit Khanna, Dr. Sushant Bhanja, Dr. Punit Bhojani and Dr. Ashwin Singh Parihar.

Topic 1

Liddle Syndrome

1.      Occurs due to gain of function mutation of ENaC (epithelial Sodium channels)
Autosomal Dominant inheritance.

2.      Since these ENaC persist independent of Mineralocorticoid stimulus, Sodium is constantly reabsorbed with loss of Potassium and Protons.

3.      Hence, Serum Sodium is high, with a low potassium and alkalosis. This is also referred to as Hypokalemic Hypertension

4.      In response to the dyselectrolemic changes, renin is suppressed, thereby lowering levels of aldosterone.

5.      Now, this state is a low aldosterone state, but looking at the dyselectrolemias, it looks as if the aldosterone levels are high, hence the name PSEUDO-hyperaldosteronism.

6.      For treatment, all we need is to inhibit these ENaC, for which we use Potassium sparing diuretics like Amiloride/Triamterene. 

Topic 2

MEN syndromes          

MEN1 (WERMER SYNDROME)

1.      Mutation at Chromosome 11q of MENIN (tumor suppressor gene)

2.      Inheritance - AD / sporadic.

3.      Primary glands involved - Pituitary, Parathyroid, Pancreas.

4.      Parathyroid(most common inv) - hypercalcemia due to adenoma.

5.      Pituitary- Ant pituitary adenoma - most commonly producing prolactin.

6.      Entropancreatic tumors- gastrinoma(most common), insulinoma, vipoma, ppoma, glucagonoma.

7.      Other associated tumors- adrenocortical tumors, foregut carcinoids, lipoma, angiofibroma,  collagenoma, meningioma, pheochronocytoma(rare)

MEN2 (SIPPLE SYNDROME)

1.      Mutation of RET protooncogene at Chr 10.

2.      MEN2A- Medullary Ca Thyroid(most common), pheochromocytoma(maybe B/L), parathyroid adenoma(milder than in MEN1). Associated with hirschsprung disease, cutaneous lichen amyloidosis.

3.      MEN2B - MTC, Pheochromocytoma( both more aggressive than in MEN2A). Associated with marfanoid habitus, ganglioneuromas and megacolon.

4.      FMTC - only medullary ca thyroid.

MEN4

1.      Chr12 mutation.

2.      Parathyroid adenoma + Pituitary adenoma + Reproductive tumors
Asso with renal, adrenal tumors.

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Pros of Online PG Medical Coaching

Preparing for entrance exams has always been a herculean task for most of the aspirants; especially when an ocean of information is available at hand for exams like PG medical entrance. Apart from the syllabus books, class notes, students receive a lot of download from the coaching institutes they join too. Don’t you think that’s a little too much pressure on the brains? In the process, students usually do not learn and end up mugging, thus defeating the purpose of education.

The purpose of this blog is to educate aspirants about how online PG medical coaching can do well to them and save a lot of time and resources. There are plenty of online PG medical coaching that not only guarantee best practice papers, but also promise definite selection in the ALL India Medical PG exam. They key here is to weigh 2-3 such platforms and opt for the one you are most comfortable with. For example: MyPGMEE is one of the most authentic platforms we have so far come across. Authored by aces like Dr. Mudit Khanna, it allows you to take medical PG entrance online tests and assess your preparation for the All India Medical PG exam.

By using online PG medical coaching like MyPGMEE, you can prepare for All India medical PG exam in the most efficient way. It not only provides simulated medical PG entrance online tests, which prepare you for the actual exam environment; it also allows you to compare your performance with your peers to check your ranking among them. Apart from this, the platform gives you access to over 12000 All India medical PG exam questions along with the most authentic answers. With this, online PG medical coaching like MyPGMEE also gives you the flexibility to study as per your convenience and pace.

With online PG medical coaching, you just have to log in from your place and time of convenience. Thus, not requiring many efforts to commute from one place to another, it helps you save your energy and a lot of money. MyPGMEE offers a number of packages and you may opt for the one which suits your requirements the best.

Also, MyPGMEE allows you both antegrade and retrograde style of studying. You can prepare for All India Medical PG exam subject wise too. You can bookmark difficult questions and come back in future for reference and revision. Too much to ask for isn’t it? And to add to the benefits, you can opt for the difficulty level while taking medical PG entrance online tests on MyPGMEE.

For more information on the tool, visit www.MyPGMEE.com. Apart from that, in case you come across any other helpful online PG medical coaching, do share your feedback. All the best for your preparation.